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Hepatitis B & hepatitis C in HIV-infection.
Shyam Kottilil, Julia O. Jackson & Michael A. Polis.
Indian J Med Res 121, April 2005, pp 424-450.
SUMMARY
Human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) are the three most common chronic viral infections seen in the world. All three viruses share modes
of transmission and hence co-exist in the same host at significantly high rates. HIV-induced immunosuppression has deleterious effects on the natural history, pathophysiology, diagnosis,
therapeutic responses to hepatitis viruses. Responses to HBV vaccination are impaired in persons with HIV infection. Co-infection with the hepatitis viruses and HIV is likely to become a major health care catastrophe in the coming years. This review discusses the current trends in the
understanding of the biology of co-infection and implications for treating these viruses effectively.
Key Words
HBV - HCV - HIV - highly active antiretroviral therapy (HAART).
