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Cardiac Dysfunction in HIV Infected Children : A Pilot Study.
Ira Shah, S.S. Prabhu, Sumitra V. and H.S. Shashikiran.
Indian Pediatrics, February 17, 2005 Volume 42.
ABSTRACT
Twenty six perinatally acquired HAART-naïve HIV positive children asymptomatic for cardiac disease in age group of 1-9 years were evaluated for cardiac abnormalities by echocardiography. All children were classified according to the revised CDC classification for HIV infection in
children. 20 (76.9%) patients had evidence of cardiac abnormalities on echocardiography. 18 (69.2%) patients in category B had statistically significant abnormal echocardiographic finding
(p<0.02). The commonest echocardiographic abnormalities seen were left ventricular dilatation in
10 (38.5%) and left ventricular hypertrophy in 10 (38.5%) patients. Echocardiographic abnormalities are present even in HIV-infected children who are asymptomatic for cardiac
dysfunction.
Key Words
Acquired immunodeficiency syndrome, Human immunodeficiency virus,
Echocardiography.
